Femara 2.5mg Tabs. 30`s

Femara Ingredients and Usage

The active ingredient is Letrozole, a potent non-steroidal aromatase inhibitor. One 2.5mg tablet is taken once daily, with or without food, for the prescribed duration of treatment.

Femara is clinically indicated for:

• Adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer

• Extended adjuvant treatment following standard tamoxifen therapy

• First-line treatment in postmenopausal women with advanced breast cancer

• Ovulation induction in fertility treatments (off-label use)

How Does Femara Work?

Femara provides anti-estrogen effects through competitive aromatase inhibition:

1. Aromatase Inhibition: Competitively binds to aromatase enzyme complex

2. Estrogen Synthesis Blockade: Inhibits conversion of androgens to estrogen throughout the body

3. Estrogen Suppression: Reduces circulating estrogen levels by 97-99%

4. Tumor Growth Prevention: Suppresses estrogen-dependent tumor cell proliferation

Femara Side Effects and Warnings

Common side effects include hot flashes, fatigue, joint pain, headache, nausea, and increased sweating. Bone pain and arthralgia are frequently reported.

Serious Considerations

1. Osteoporosis Risk: Accelerates bone mineral density loss - regular bone monitoring required

2. Cardiovascular Events: Increased incidence of hypercholesterolemia and cardiovascular events

3. Hepatic Impairment: Use with caution in patients with severe liver dysfunction

4. Drug Interactions: Avoid concomitant use with estrogen-containing therapies

5. Pregnancy Risk: Contraindicated in pregnant and premenopausal women

Femara Storage Conditions

Femara Tablets require proper storage conditions:

• Store below 30°C in original packaging

• Protect from moisture and light

• Keep blister strips sealed until use

• Keep out of reach of children

• Do not use after expiration date