Lezra Excel 2.5mg Tab 30`s

Doctors prescribe it for tumours that depend on estrogen to grow, and to prevent cancer returning after surgery.

Lezra Excel 2.5mg Ingredients and Usage

Lezra Excel 2.5mg Tablet contains letrozole, a non steroidal aromatase inhibitor used in hormonal breast cancer therapy. An aromatase inhibitor is a drug that blocks the enzyme responsible for making estrogen in the body. Doctors prescribe Lezra Excel 2.5mg Tablet for postmenopausal women with hormone receptor positive breast cancer.

Lezra Excel 2.5mg Tablet treats early breast cancer after surgery and advanced disease that has spread. It also helps prevent the cancer returning in women who have completed other hormonal treatment. Patients take one Lezra Excel 2.5mg Tablet by mouth once daily, with or without food, as the doctor directs.

How Does Lezra Excel 2.5mg Work?

Lezra Excel 2.5mg Tablet works by blocking aromatase, the enzyme that converts androgen hormones into estrogen. Many breast tumours rely on estrogen as fuel, so they grow faster when estrogen levels stay high. By inhibiting aromatase, Lezra Excel 2.5mg Tablet lowers circulating estrogen across the whole body.

This drop in estrogen starves hormone receptor positive tumours and slows or halts their growth. Lezra Excel 2.5mg Tablet therefore causes estrogen dependent breast tumours to shrink and regress over time. The letrozole in each tablet targets estrogen production specifically, sparing the body other steroid hormones.

Lezra Excel 2.5mg Side Effects

Lezra Excel 2.5mg Tablet commonly causes hot flashes, joint pain, and fatigue because it lowers estrogen levels. Most effects stay mild, but patients should report any that persist or worsen to their doctor.

• Hot flashes and night sweats

• Joint pain, stiffness, and muscle aches (arthralgia and myalgia)

• Fatigue, weakness, and dizziness

• Bone thinning, raising the risk of osteoporosis and fractures

• Raised blood cholesterol levels

• Nausea, headache, and difficulty sleeping

• Hair thinning and swelling of the hands or feet

Warnings

• Lezra Excel 2.5mg Tablet is contraindicated in pregnancy, since letrozole can cause birth defects and miscarriage.

• Premenopausal women and breastfeeding mothers must not take Lezra Excel 2.5mg Tablet without specialist guidance.

• Long term use lowers bone density, so doctors monitor bone health and may add a bisphosphonate.

• Patients with severe liver impairment or cirrhosis need a lower dose and close medical supervision.

• Lezra Excel 2.5mg Tablet can raise cholesterol, so the doctor checks lipid levels during treatment.

• Pregnant women should avoid handling crushed or broken tablets, as letrozole can absorb through the skin.

Lezra Excel 2.5mg Storage Conditions

Store Lezra Excel 2.5mg Tablet below 30°C in a cool, dry place away from heat and direct sunlight. Keep the tablets in their original blister pack to protect them from moisture and light until use. Store Lezra Excel 2.5mg Tablet out of the reach of children and do not use it past the printed expiry date.