Arimidex 1mg (28 Tablets)
Arimidex 1mg Tablet contains anastrozole, a nonsteroidal aromatase inhibitor used to treat hormone receptor positive breast cancer in postmenopausal women. Buy Arimidex 1mg Tablet, pack of 28, at PakMeds with a valid prescription for genuine ICI Pakistan stock.
Overview
Doctors prescribe it as first line therapy for advanced disease and as adjuvant treatment after surgery or radiation.
Manufacturer | ICI Pakistan Ltd (AstraZeneca licensed) |
|---|---|
Active Ingredient(s) | Anastrozole |
Strength | 1mg |
Pack Size | 28 tablets |
Prescription Required | Yes |
Generic Name(s) | Anastrozole |
Arimidex 1mg Tablet Ingredients and Usage
Arimidex 1mg Tablet contains anastrozole, a nonsteroidal aromatase inhibitor belonging to the hormonal anticancer drug class. Doctors prescribe it as first line therapy for postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer.
Arimidex 1mg Tablet also treats advanced breast cancer that has progressed after tamoxifen therapy, and is used as preventive treatment in postmenopausal women at moderate to high risk of developing breast cancer. It is taken once daily, with or without food.
How Does Arimidex 1mg Tablet Work?
Anastrozole selectively and reversibly binds to aromatase, the enzyme responsible for converting androstenedione and testosterone into estrone and estradiol, two forms of estrogen. In postmenopausal women, this pathway is the primary source of circulating estrogen.
By blocking aromatase, Arimidex 1mg Tablet significantly lowers estrogen levels throughout the body without affecting other hormone pathways. This reduces stimulation of estrogen receptors on hormone receptor positive breast cancer cells, slowing or stopping their growth.
Arimidex 1mg Tablet Side Effects
Arimidex 1mg Tablet commonly causes menopause like symptoms and musculoskeletal discomfort, since it significantly lowers estrogen levels.
Hot flashes
Joint pain and stiffness
Fatigue
Nausea
Headache
Weakness
Bone thinning over time
Warnings
Arimidex 1mg Tablet increases the risk of ischemic cardiovascular events, including heart attack, in women with pre-existing ischemic heart disease; discuss cardiac risk factors with a doctor before starting treatment.
The medicine can reduce bone mineral density and increase fracture risk; bone density testing may be needed during treatment, and it is not suitable for women with severe osteoporosis.
Arimidex 1mg Tablet is contraindicated in pregnancy and breastfeeding, since it can cause fetal harm; effective contraception is required during treatment and for at least three weeks after the last dose.
This medicine is intended for postmenopausal women only and is contraindicated in premenopausal women, including those still menstruating.
Do not combine Arimidex 1mg Tablet with tamoxifen or estrogen containing therapies, since these reduce its effectiveness or interfere with its mechanism.
Serious allergic reactions, including anaphylaxis and angioedema, and rare severe skin reactions such as Stevens-Johnson syndrome have been reported.
Use with caution in patients with severe liver or kidney impairment, since anastrozole has not been extensively studied in these populations.
Arimidex 1mg Tablet Storage Conditions
Store Arimidex 1mg Tablet at controlled room temperature between 20°C and 25°C, protected from moisture and light. Keep tablets in their original packaging until the dose is due. Store this medicine out of reach of children and pets, and dispose of any expired or unused tablets according to local pharmacy guidelines.
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