Palbonix 100mg (Palbociclib)
Palbonix 100mg is a prescription oncology medicine containing Palbociclib, used in combination with hormone therapies to treat certain types of advanced or metastatic breast cancer.
Imported medicine — supplied under DRAP NOC. Arranged on demand through the No Objection Certificate process of the Drug Regulatory Authority of Pakistan, only for patients with a valid prescription who complete identity verification. Non-returnable once dispensed. Learn more about NOC orders →
Overview
Palbonix 100mg is an advanced oncology medication containing the active ingredient Palbociclib. It is prescribed for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body. This targeted therapy is available through PakMeds for patients across Pakistan.
Important Information
Prescription medicine: Palbonix is supplied only against a valid prescription from a registered doctor. Use it only as directed by your doctor.
NOC medicine: Palbonix is only available to patients willing to complete identity verification and the NOC (No Objection Certificate) process. It is arranged on demand against a valid prescription.
Key Benefits of Palbonix
Targets specific proteins to help slow down the division and growth of cancer cells.
Works in combination with endocrine therapies to improve progression-free survival.
Provides an oral treatment option for advanced or metastatic breast cancer.
Helps delay the need for starting aggressive chemotherapy regimens.
Palbonix Ingredients and Usage
Palbonix contains Palbociclib, which belongs to a class of medications known as cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors. It is specifically indicated for the treatment of postmenopausal women, and men, with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer.
This medicine is used in combination with an aromatase inhibitor as initial endocrine-based therapy, or with fulvestrant in patients whose disease has progressed after receiving previous endocrine therapy. Your oncologist will determine the exact combination regimen suitable for your specific diagnosis.
How Does Palbonix Work?
Palbociclib works by blocking two specific proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins are highly active in certain cancer cells, causing them to grow and divide too quickly. By inhibiting CDK4/6, Palbonix helps stop the progression of the cell cycle, thereby slowing down or halting the growth of the breast cancer cells.
How to Use Palbonix
Palbonix is an oral capsule that must be swallowed whole with food. Do not chew, crush, or open the capsules before swallowing.
It is highly recommended to take this medication at approximately the same time every day to maintain consistent levels in your body.
Your oncologist will determine the appropriate treatment cycle and duration. Always follow their precise instructions and do not alter your schedule without consulting them.
Palbonix Side Effects
Like all oncology medications, Palbonix can cause side effects. Please monitor your health closely and contact your doctor immediately if you notice any new, worsening, or severe symptoms.
Decreased white blood cell count (neutropenia)
Anemia (low red blood cell count)
Thrombocytopenia (low blood platelet count)
Fatigue and extreme tiredness
Nausea and vomiting
Diarrhea or constipation
Hair thinning or hair loss (alopecia)
Loss of appetite
Skin rash
Warnings
Palbonix can cause severe neutropenia, which significantly increases your risk of developing serious or life-threatening infections.
There is a risk of developing interstitial lung disease or pneumonitis, which can be severe or fatal.
Regular blood tests must be performed before and during treatment to monitor your complete blood count.
This medicine can cause fetal harm and must not be taken during pregnancy.
Precautions and Who Should Avoid It
Inform your doctor if you have a history of liver or kidney disease before starting this medication.
Tell your healthcare provider about any current signs of infection, such as a fever, chills, or sore throat.
Effective non-hormonal contraception must be used by both female and male patients during treatment and for several months after the final dose.
Do not breastfeed while taking Palbonix and for a specified period after your last dose.
Avoid receiving live vaccines while undergoing treatment with Palbociclib.
Drug and Food Interactions
Avoid consuming grapefruit or grapefruit juice, as it can increase the concentration of Palbociclib in your blood.
Strong CYP3A inhibitors, such as certain antifungals or antivirals, can increase the risk of side effects and should be avoided.
Strong CYP3A inducers, such as rifampin or St. John's Wort, can reduce the effectiveness of this medicine.
Inform your doctor about all prescription medicines, over-the-counter drugs, and herbal supplements you are currently taking.
Palbonix Storage Conditions
Store Palbonix in its original packaging to protect it from moisture. Keep the container tightly closed and store it as directed on the label, away from direct heat, moisture, and sunlight. Always keep this and all other medications out of the reach of children.
Customer Reviews
No reviews yet. Be the first to review this product!
Login to write a review
