Gammaras 5% Intravenous Immunoglobulin (IVIG)
Gammaras is only available on NOC. This product is not commercially available and is only for patients who are willing to go through the required steps vetted by their doctor.
Overview
| Manufacturer | Kamada Ltd. / Local Distributors |
| Active Ingredients | Human Normal Immunoglobulin (IgG) |
| Medicine Strength | 5% solution (50mg per ml) in various vial sizes |
| Formulation | Solution for Intravenous Infusion |
| Requires Prescription? | Yes (Hospital Use - Immunologist or Specialist prescription required) |
| Generics | Intravenous Immunoglobulin (IVIG) |
Gammaras Ingredients and Usage
Primary immunodeficiency syndromes
Secondary immunodeficiencies with impaired antibody production
Immune thrombocytopenic purpura (ITP)
Guillain-Barré syndrome and other neuroimmunological disorders
Kawasaki disease and various autoimmune conditions
How Does Gammaras Work?
Antibody Replacement: Provides broad-spectrum IgG antibodies for immunodeficient patients
Fc Receptor Blockade: Blocks Fc receptors on macrophages in immune thrombocytopenia
Anti-inflammatory Action: Modulates complement activation and cytokine production
Autoantibody Neutralization: Neutralizes pathogenic autoantibodies in autoimmune diseases
Gammaras Side Effects and Warnings
Serious Considerations
Anaphylaxis: May cause severe hypersensitivity reactions, especially in IgA-deficient patients
Thromboembolic Events: Increased risk of thrombosis, stroke, and myocardial infarction
Aseptic Meningitis: Can cause aseptic meningitis syndrome within 72 hours of infusion
Renal Impairment: May cause acute renal failure, especially with sucrose-containing products
Hemolytic Reactions: Can cause hemolysis due to passive transfer of blood group antibodies
Gammaras Storage Conditions
Store at 2°C to 8°C in refrigerator
Do not freeze - protect from light
Keep in original carton until use
Use immediately after opening
Do not use if cloudy, discolored, or contains particles
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