Epinor 8mg/4ml IV Inj. 10`s

Manufacturer	Various Manufacturers
Active Ingredients	Noradrenaline Acid Tartrate (Norepinephrine)
Medicine Strength	8mg per ampoule (equivalent to 4mg Noradrenaline base)
Formulation	Solution for Intravenous Infusion
Requires Prescription?	Yes (Hospital Use Only - Critical Care Specialist)
Generics	Noradrenaline, Norepinephrine

Epinor Ingredients and Usage

The active ingredient is Noradrenaline Acid Tartrate, a potent catecholamine vasopressor. It is administered as a continuous intravenous infusion after dilution, with dosage titrated to maintain target blood pressure.Epinor is clinically indicated for:

• Acute hypotension in shock states (septic, cardiogenic, neurogenic)

• Blood pressure control in perioperative settings

• Emergency treatment of severe hypotension unresponsive to fluid resuscitation

• Life-threatening low blood pressure conditions

How Does Epinor Work?

Epinor provides rapid vasopressor action through adrenergic receptor stimulation:

1. Alpha-1 Receptor Agonism: Causes potent vasoconstriction of peripheral vessels

2. Blood Pressure Elevation: Increases systemic vascular resistance and mean arterial pressure

3. Beta-1 Receptor Stimulation: Has moderate inotropic and chronotropic cardiac effects

4. Coronary Blood Flow: May increase coronary artery blood flow

Epinor Side Effects and Warnings

Common side effects include anxiety, headache, tremor, palpitations, and bradycardia. Most effects are dose-dependent and managed by infusion rate adjustment.

Serious Considerations

1. Extravasation Risk: May cause severe tissue necrosis - administer through central line

2. Cardiac Arrhythmias: May precipitate serious ventricular arrhythmias

3. Hypertensive Crisis: Can cause severe hypertension if overdosed

4. Ischemic Injury: May reduce organ perfusion despite increased blood pressure

5. Drug Interactions: MAOIs and TCAs can potentiate pressor effects significantly

Epinor Storage Conditions

Epinor Injection requires careful storage and handling:

• Store below 25°C protected from light

• Keep ampoules in original carton until use

• Protect from freezing

• Use immediately after dilution

• Discard any unused portion