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Epinor 8mg/4ml IV Inj. 10`s

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Overview

ManufacturerVarious Manufacturers
Active IngredientsNoradrenaline Acid Tartrate (Norepinephrine)
Medicine Strength8mg per ampoule (equivalent to 4mg Noradrenaline base)
FormulationSolution for Intravenous Infusion
Requires Prescription?Yes (Hospital Use Only - Critical Care Specialist)
GenericsNoradrenaline, Norepinephrine

Epinor Ingredients and Usage

The active ingredient is Noradrenaline Acid Tartrate, a potent catecholamine vasopressor. It is administered as a continuous intravenous infusion after dilution, with dosage titrated to maintain target blood pressure.Epinor is clinically indicated for:
  • Acute hypotension in shock states (septic, cardiogenic, neurogenic)

  • Blood pressure control in perioperative settings

  • Emergency treatment of severe hypotension unresponsive to fluid resuscitation

  • Life-threatening low blood pressure conditions

How Does Epinor Work?

Epinor provides rapid vasopressor action through adrenergic receptor stimulation:
  1. Alpha-1 Receptor Agonism: Causes potent vasoconstriction of peripheral vessels

  2. Blood Pressure Elevation: Increases systemic vascular resistance and mean arterial pressure

  3. Beta-1 Receptor Stimulation: Has moderate inotropic and chronotropic cardiac effects

  4. Coronary Blood Flow: May increase coronary artery blood flow

Epinor Side Effects and Warnings

Common side effects include anxiety, headache, tremor, palpitations, and bradycardia. Most effects are dose-dependent and managed by infusion rate adjustment.

Serious Considerations

  1. Extravasation Risk: May cause severe tissue necrosis - administer through central line

  2. Cardiac Arrhythmias: May precipitate serious ventricular arrhythmias

  3. Hypertensive Crisis: Can cause severe hypertension if overdosed

  4. Ischemic Injury: May reduce organ perfusion despite increased blood pressure

  5. Drug Interactions: MAOIs and TCAs can potentiate pressor effects significantly

Epinor Storage Conditions

Epinor Injection requires careful storage and handling:
  • Store below 25°C protected from light

  • Keep ampoules in original carton until use

  • Protect from freezing

  • Use immediately after dilution

  • Discard any unused portion

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