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Edonax Injection 5mg/100 ml
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Overview
| Manufacturer | High-Q Pharmaceuticals Pakistan |
| Active Ingredients | Drotaverine Hydrochloride |
| Medicine Strength | 5mg per 100mL (0.05mg/mL) |
| Formulation | Solution for Intravenous Infusion |
| Requires Prescription? | Yes (Hospital/Emergency use) |
| Generics | Drotaverine |
Edonax Ingredients and Usage
The active ingredient is Drotaverine Hydrochloride, a papaverine derivative antispasmodic. The 5mg/100mL solution is administered as slow intravenous infusion for acute spasms.
Edonax is clinically indicated for:
- Renal colic and ureteric spasm relief
- Biliary colic and gallbladder spasms
- Gastrointestinal smooth muscle spasms
- Gynecological spasms and dysmenorrhea
How Does Edonax Work?
Edonax provides smooth muscle relaxation through phosphodiesterase inhibition:
- PDE-4 Inhibition: Selectively inhibits phosphodiesterase type 4 enzyme
- cAMP Elevation: Increases intracellular cyclic adenosine monophosphate
- Muscle Relaxation: Reduces calcium influx into smooth muscle cells
- Selective Action: Primarily affects smooth muscle without cardiac effects
Edonax Side Effects and Warnings
Common side effects include hypotension, dizziness, headache, and injection site reactions. Most effects are mild and transient.
Serious Considerations
- Hypotension Risk: May cause significant blood pressure drop
- Cardiac Patients: Use with caution in severe heart failure
- Hepatic Impairment: Dose adjustment needed in liver disease
- Renal Function: Monitor in patients with kidney impairment
- Pregnancy: Use only if clearly needed during pregnancy
Edonax Storage Conditions
Edonax Injection requires proper storage handling:
- Store at room temperature below 25°C
- Protect from light and freezing
- Use opened infusion bags immediately
- Discard if solution appears discolored or contains particles
- Keep out of reach of children
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