Zytux 100mg Injection 2s

This biosimilar antibody targets and clears the B cells that drive these conditions.

Zytux 100mg Injection Ingredients and Usage

Zytux 100mg Injection contains rituximab, a CD20 directed cytolytic monoclonal antibody. This antibody class targets and destroys B lymphocytes, the white blood cells behind many cancers and autoimmune diseases. Oncologists prescribe Zytux for CD20 positive B cell non Hodgkin lymphoma and chronic lymphocytic leukemia.

Zytux also treats autoimmune conditions when combined with other medicines. Doctors use Zytux with methotrexate for active rheumatoid arthritis and with glucocorticoids for vasculitis. A healthcare professional gives Zytux as a slow intravenous infusion, with the dosing schedule set by the condition treated.

How Does Zytux 100mg Injection Work?

Zytux works by binding to CD20, a protein found on the surface of B lymphocytes. CD20 appears on more than 90 percent of B cell non Hodgkin lymphomas, which makes it a precise target. By attaching to this protein, Zytux marks the B cells for destruction.

Zytux then triggers two immune pathways, complement dependent cytotoxicity and antibody dependent cell mediated cytotoxicity. These pathways break down the tagged B cells and clear them from the blood and tissues. This targeted B cell depletion shrinks tumours and calms the immune attack in autoimmune disease.

Zytux 100mg Injection Side Effects

Zytux most often causes infusion reactions such as fever and chills, especially during the first dose. Doctors usually give medicines beforehand to reduce these reactions.

• Fever, chills, and rigors during infusion

• Headache and fatigue or weakness

• Nausea and vomiting

• Low blood pressure and flushing

• Itching, rash, and hives

• Increased risk of infections

• Low white blood cell and platelet counts

Warnings

• Zytux carries a boxed warning for fatal infusion reactions, with most fatal cases occurring during the first infusion.

• Zytux carries a boxed warning for severe mucocutaneous reactions, including skin blistering that can be fatal.

• Zytux can reactivate hepatitis B virus, sometimes causing liver failure and death, so doctors screen for hepatitis B first.

• Zytux carries a boxed warning for progressive multifocal leukoencephalopathy, a rare and often fatal brain infection.

• Zytux can harm the fetus and is not recommended during pregnancy, so patients must use contraception during treatment.

• Doctors avoid Zytux in patients with severe active infections and monitor blood counts and immune function throughout treatment.

Zytux 100mg Injection Storage Conditions

Store Zytux vials in a refrigerator at 2°C to 8°C and protect them from direct sunlight to keep the rituximab stable. Never freeze or shake Zytux, as both actions damage the antibody and make the medicine unsafe to use. Keep the vials out of the reach of children, and let a healthcare professional handle dilution and storage of the prepared infusion.