Vinblas 10mg Inj (Vinblastine Sulphate)
Vinblas 10mg Injection treats Hodgkin lymphoma, non Hodgkin lymphoma, and several other cancers. Order Vinblas 10mg Injection at PakMeds for authentic, prescription verified delivery.
Overview
Oncologists prescribe it as part of combination chemotherapy for adult and pediatric patients.
Manufacturer | Pharmedic |
|---|---|
Active Ingredient(s) | Vinblastine Sulfate |
Strength | 10mg |
Pack Size | 1 vial |
Prescription Required | Yes |
Generic Name(s) | Vinblastine Sulfate |
Vinblas Ingredients and Usage
Vinblas 10mg Injection contains vinblastine sulfate, a vinca alkaloid derived from the periwinkle plant Catharanthus roseus. Oncologists use it to treat Hodgkin lymphoma, non Hodgkin lymphoma, and testicular cancer. Doctors also prescribe it for breast cancer, histiocytosis, and methotrexate resistant choriocarcinoma.
Vinca alkaloids belong to the antineoplastic drug class and target rapidly dividing cells. Vinblas is administered by intravenous injection only, usually as part of a combination chemotherapy regimen. A qualified oncology team must supervise every dose.
How Does Vinblas Work?
Vinblastine binds to tubulin, the protein subunit that forms microtubules inside dividing cells. This binding blocks microtubule formation in the mitotic spindle, the structure chromosomes need to separate during cell division.
Without a functioning spindle, cancer cells arrest at the metaphase stage of mitosis and cannot complete division. The arrested cells eventually undergo apoptosis, or programmed cell death, which shrinks the tumor over successive treatment cycles.
Vinblas Side Effects
Vinblas commonly affects the bone marrow and digestive system because it targets fast dividing cells throughout the body. Report severe or persistent symptoms to your oncologist right away.
Low white blood cell count, raising infection risk
Nausea, vomiting, and constipation
Hair loss
Fatigue and general weakness
Injection site pain or irritation
Peripheral neuropathy with numbness or tingling
Fever and chills
Warnings
Vinblas is contraindicated in patients with significant granulocytopenia unless the low count results from the cancer itself
Do not start treatment during an active bacterial infection; control the infection first
Vinblas is fatal if given intrathecally; administer by intravenous route only
Use with extreme caution in patients with impaired kidney function
Avoid use during pregnancy, since vinblastine can cause fetal harm
Breastfeeding mothers should not use this medicine
Liver impairment can increase toxicity, since the biliary system clears much of the drug
Avoid alcohol and driving while receiving treatment
Vinblas Storage Conditions
Store Vinblas 10mg Injection in a refrigerator between 2°C and 8°C, and never freeze the vial. Protect the injection from light and keep it in its original carton until use. Keep the vial out of reach of children, and dispose of used vials according to cytotoxic waste guidelines rather than household trash.
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