Trexate 50mg Inj 2ml

Doctors prescribe it when oral therapy fails or when a faster, more reliable dose is needed.

Trexate Ingredients and Usage

Trexate 50mg Injection 2ml contains methotrexate, a folic acid antagonist from the antimetabolite drug class. Oncologists use it to treat leukemia, lymphoma, osteosarcoma, breast cancer, and gestational trophoblastic disease.

Rheumatologists and dermatologists also prescribe Trexate for severe rheumatoid arthritis and psoriasis that has not responded to other treatments. In these conditions the injection slows immune cell growth and skin cell proliferation. A doctor administers Trexate by intramuscular or intravenous route.

How Does Trexate Work?

Methotrexate inhibits dihydrofolate reductase, an enzyme the body needs to make tetrahydrofolate. Tetrahydrofolate supplies the building blocks for purine and pyrimidine synthesis, which cells use to construct new DNA and RNA.

By blocking this enzyme, Trexate stops rapidly dividing cells from making genetic material and prevents them from multiplying. This action slows cancer growth and calms the overactive immune response seen in rheumatoid arthritis and psoriasis.

Trexate Side Effects

Trexate affects fast growing cells throughout the body, so side effects commonly involve the blood, liver, and digestive tract. Contact your doctor promptly if any symptom becomes severe.

• Nausea, vomiting, and mouth sores

• Fatigue and general weakness

• Hair thinning or hair loss

• Low white blood cell and platelet counts

• Elevated liver enzymes

• Dizziness or blurred vision

• Injection site irritation

Warnings

• Trexate is contraindicated in patients with known hypersensitivity to methotrexate

• Avoid use in pregnancy, since methotrexate can cause serious birth defects

• Breastfeeding mothers should not receive this injection

• Do not use in severe kidney or liver disease, or in active peptic ulcer disease

• Avoid Trexate during active infections or significant bone marrow suppression

• Regular monitoring of liver function and blood counts is required during treatment

• Avoid alcohol, as it raises the risk of liver toxicity

• Do not drive until you know how the injection affects your vision and alertness

Trexate Storage Conditions

Store Trexate 50mg Injection 2ml below 30°C in a cool, dry place and protect the vial from direct light. Do not freeze the solution. Keep the injection in its original packaging and out of reach of children, and dispose of used vials as cytotoxic waste rather than household trash.