Thalido 100 M g Newww

Doctors prescribe it alone or alongside other cancer medicines such as dexamethasone.

Thalido 100mg Ingredients and Usage

Thalido 100mg contains thalidomide, a synthetic glutamic acid derivative that belongs to the immunomodulatory drug class. Doctors prescribe it for multiple myeloma, a cancer of plasma cells in the bone marrow, usually combined with dexamethasone.

Thalido 100mg also treats erythema nodosum leprosum, an inflammatory skin reaction that occurs in leprosy patients. It reduces painful nodules and systemic inflammation linked to this condition. Specialists sometimes prescribe it off label for other inflammatory or autoimmune skin disorders under close medical supervision.

How Does Thalido 100mg Work?

Thalidomide inhibits tumor necrosis factor alpha, a signaling protein that drives inflammation throughout the body. Cereblon, a protein thalidomide binds to directly, mediates this immunomodulatory action.

Thalido 100mg also blocks angiogenesis, the process that forms new blood vessels feeding tumor tissue. By limiting blood supply to abnormal plasma cells, it slows multiple myeloma progression. The drug additionally boosts natural killer cell activity, strengthening the body's response against cancer cells.

Thalido 100mg Side Effects

Thalido 100mg commonly causes sedation and mild to moderate discomfort during early treatment. Most side effects lessen once the body adjusts to the dose.

• Drowsiness and sleepiness

• Constipation

• Peripheral neuropathy, numbness or tingling in hands and feet

• Skin rash

• Dizziness

• Dry mouth and dry skin

• Weight gain and increased appetite

Warnings

• Thalido 100mg is strictly contraindicated in pregnancy. It causes severe birth defects including phocomelia and limb absence, even after a single dose.

• Women of childbearing age must confirm a negative pregnancy test and use two reliable contraceptive methods before and during treatment.

• Male patients must use condoms during treatment, since thalidomide passes into semen and can cause fetal harm through a partner.

• Thalido 100mg increases the risk of deep vein thrombosis and pulmonary embolism, particularly in multiple myeloma patients on combination therapy.

• Avoid combining Thalido 100mg with other sedating drugs, such as benzodiazepines or opioids, as this raises the risk of excessive drowsiness.

• Use with caution in patients with a history of peripheral neuropathy or thyroid dysfunction, since thalidomide can worsen these conditions.

• Thalido 100mg is dispensed only against a valid prescription and requires ongoing monitoring by a physician.

Thalido 100mg Storage Conditions

Store Thalido 100mg capsules at room temperature between 20°C and 25°C, away from direct sunlight and moisture. Keep the strip in its original packaging to protect capsules from humidity, and avoid refrigeration. Store this medicine strictly out of reach of children and away from anyone who is pregnant or may become pregnant, given its severe teratogenic risk.