Lenaido 10mg Capsule 10S

Doctors prescribe it under strict pregnancy prevention protocols due to its severe teratogenic risk.

Lenaido 10mg Capsule Ingredients and Usage

Lenaido 10mg Capsule contains lenalidomide, an immunomodulatory agent belonging to the thalidomide analogue drug class. Doctors prescribe it as standard therapy for newly diagnosed and relapsed or refractory multiple myeloma, usually combined with dexamethasone.

Lenaido 10mg Capsule also reduces transfusion dependence in myelodysplastic syndromes linked to a chromosome 5q deletion, and treats relapsed or refractory mantle cell lymphoma, follicular lymphoma, and marginal zone lymphoma. A hematologist or oncologist must supervise treatment throughout.

How Does Lenaido 10mg Capsule Work?

Lenalidomide binds to cereblon, a protein that forms part of an enzyme complex controlling which proteins the cell breaks down. This binding changes the complex's targets, leading to the destruction of specific proteins that cancer cells need to survive.

Beyond this direct cytotoxic effect, Lenaido 10mg Capsule modulates the immune system by enhancing natural killer cell and T cell activity against abnormal cells. It also has antiangiogenic properties, limiting the blood vessel growth that tumors depend on.

Lenaido 10mg Capsule Side Effects

Lenaido 10mg Capsule commonly causes blood count changes and general side effects. Regular monitoring helps catch these early.

• Neutropenia and thrombocytopenia

• Fatigue

• Constipation or diarrhea

• Skin rash

• Fever

• Peripheral swelling

• Nausea

Warnings

• Lenaido 10mg Capsule causes severe, life-threatening birth defects and embryo-fetal death if taken during pregnancy; pregnancy must be excluded before starting and prevented using two reliable contraceptive methods throughout treatment.

• The medicine causes significant neutropenia and thrombocytopenia; complete blood counts must be monitored weekly during early treatment and regularly thereafter.

• Lenaido 10mg Capsule significantly increases the risk of deep vein thrombosis and pulmonary embolism, particularly when combined with dexamethasone; doctors may prescribe blood thinning medication for prevention.

• Patients with multiple myeloma face an increased risk of second primary cancers with long-term lenalidomide use; this risk should be weighed against treatment benefit.

• Serious allergic and skin reactions have occurred, including angioedema, Stevens Johnson syndrome, and toxic epidermal necrolysis; stop treatment immediately if severe rash or blistering develops.

• Tumor lysis syndrome, sometimes fatal, has been reported in patients with high tumor burden; close monitoring is required at the start of treatment.

• Men taking Lenaido 10mg Capsule must use condoms during treatment, since lenalidomide passes into semen and can cause fetal harm through a partner.

Lenaido 10mg Capsule Storage Conditions

Store Lenaido 10mg Capsule at room temperature between 20°C and 25°C, away from direct sunlight and moisture. Keep capsules in their original packaging and avoid refrigeration. Store this medicine strictly out of reach of children and away from anyone who is pregnant or may become pregnant, given its severe teratogenic risk.