Tagrix 80mg Tab 30`s (Osimertinib)
Tagrix 80mg Tablets contain osimertinib, a targeted oral therapy for advanced lung cancer. Order genuine Tagrix 80mg Tablets (pack of 30) now at PakMeds with a valid prescription.
Oncologists prescribe it for EGFR mutation positive non small cell lung cancer, taken as one tablet daily. These are prescription only medications for advanced lung cancer. We do not offer or sell these products without valid prescriptions.
Manufacturer | Beacon Pharmaceuticals Ltd |
|---|---|
Active Ingredient(s) | Osimertinib (as mesylate) 80mg |
Strength | 80mg |
Pack Size | 30 Tablets |
Prescription Required | Yes |
Generic Name(s) | Osimertinib |
Tagrix 80mg Tablets Ingredients and Usage
Tagrix 80mg Tablets contain osimertinib, a third generation tyrosine kinase inhibitor that targets faulty EGFR signals. A tyrosine kinase inhibitor blocks a specific enzyme that cancer cells use to grow and divide. Osimertinib is a targeted therapy, which differs from standard chemotherapy because it acts on a precise cancer mutation.
Tagrix treats locally advanced or metastatic non small cell lung cancer that carries an EGFR mutation. Doctors prescribe it as first line therapy and for tumours with the T790M resistance mutation that escape earlier treatment. The usual dose is one 80mg tablet once daily, taken with or without food, until the disease progresses.
How Does Tagrix 80mg Tablets Work?
Tagrix 80mg Tablets work because osimertinib binds irreversibly to mutated forms of the EGFR protein on lung cancer cells. EGFR is the epidermal growth factor receptor, an enzyme that sends growth signals that drive tumour cells to multiply. By locking onto the mutated receptor, osimertinib shuts down these signals and slows cancer growth.
Osimertinib targets the EGFR mutations T790M, L858R, and exon 19 deletion at much lower doses than normal EGFR. This precision largely spares healthy EGFR, which reduces some side effects seen with older drugs. The blocked growth signal pushes the cancer cell toward death and controls disease spread.
Tagrix 80mg Tablets Side Effects
Tagrix 80mg Tablets commonly cause skin, digestive, and nail effects because EGFR also supports healthy skin cells. Report severe diarrhoea, new breathlessness, or skin blistering to your oncologist promptly.
Diarrhoea
Skin rash and dry skin
Inflammation around the nails
Mouth sores
Loss of appetite
Fatigue and weakness
Low white cell and platelet counts
Cough or breathlessness
Warnings
Osimertinib can cause interstitial lung disease, a serious lung inflammation that is sometimes fatal, so report new cough or breathlessness.
The drug can prolong the QT interval, a heart rhythm change, so doctors may order ECG and electrolyte checks.
Osimertinib can weaken the heart muscle and reduce pumping strength, which needs heart monitoring during treatment.
Severe skin reactions and eye inflammation can occur, so report blistering rashes or vision changes quickly.
Osimertinib harms the unborn baby, so patients must use effective contraception during treatment and for some weeks after.
Strong CYP3A inducer drugs lower osimertinib levels and can reduce its effect, so tell your doctor all medicines you take.
Tagrix 80mg Tablets Storage Conditions
Store Tagrix 80mg Tablets below 30°C in a cool, dry place, away from direct heat and moisture. Keep the tablets sealed in their original blister pack until use, since osimertinib can absorb moisture once exposed. Store the medicine out of reach of children, because this potent cancer drug is harmful if swallowed accidentally.
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