Intaxel 300mg/50ml Inj. 1`s
Intaxel 300mg/50ml Injection contains paclitaxel, a taxane chemotherapy agent used for breast, ovarian, and non small cell lung cancer, as well as Kaposi's sarcoma. Buy Intaxel 300mg/50ml Injection at PakMeds with a valid prescription for genuine, cold chain handled stock.
Overview
A qualified oncology team administers it as an intravenous infusion after premedication to reduce allergic reactions.
Manufacturer | ATCO Laboratories Ltd |
|---|---|
Active Ingredient(s) | Paclitaxel |
Strength | 300mg/50ml |
Pack Size | 1 vial |
Prescription Required | Yes |
Generic Name(s) | Paclitaxel |
Intaxel 300mg/50ml Injection Ingredients and Usage
Intaxel 300mg/50ml Injection contains paclitaxel, a taxane belonging to the antimicrotubule anticancer drug class. Oncologists prescribe it as first line therapy for ovarian carcinoma, usually combined with cisplatin, and as second line treatment after platinum based therapy fails.
Intaxel 300mg/50ml Injection also treats node positive breast cancer as adjuvant therapy, non small cell lung cancer, and AIDS related Kaposi's sarcoma. A specialist experienced in chemotherapy administration must supervise every infusion.
How Does Intaxel 300mg/50ml Injection Work?
Paclitaxel promotes the assembly of microtubules from tubulin dimers and stabilizes the resulting structure by preventing depolymerization. Microtubules normally disassemble and reassemble to allow cell division to proceed.
By locking microtubules in place, Intaxel 300mg/50ml Injection blocks the normal dynamic reorganization needed for mitosis. This arrests cancer cells during cell division and triggers cell death, slowing tumor growth across multiple cancer types.
Intaxel 300mg/50ml Injection Side Effects
Intaxel 300mg/50ml Injection commonly causes blood count changes and nerve related side effects. Close monitoring during and after infusion is standard practice.
Low white blood cell count, raising infection risk
Peripheral neuropathy, numbness or tingling in hands and feet
Hair loss
Joint and muscle pain
Nausea and vomiting
Fatigue
Mouth sores
Warnings
Intaxel 300mg/50ml Injection can cause severe hypersensitivity reactions, including fatal anaphylaxis, even after standard premedication with corticosteroids, antihistamines, and H2 blockers.
Do not restart treatment in patients who have experienced a severe hypersensitivity reaction to paclitaxel.
Avoid use in patients with a baseline neutrophil count below 1,500 cells per cubic millimeter, since this raises the risk of serious infection.
Intaxel 300mg/50ml Injection is not recommended in pregnancy, since it may harm an unborn baby; men and women should use reliable contraception during treatment.
Avoid aspirin or aspirin containing products unless specifically approved by the treating doctor.
Use with caution in patients with impaired liver or kidney function, since dose adjustment may be required.
Avoid alcohol during treatment, and report any signs of infection, unusual bruising, or bleeding to the doctor immediately.
Intaxel 300mg/50ml Injection Storage Conditions
Store unopened vials of Intaxel 300mg/50ml Injection between 20°C and 25°C, protected from light. Keep the vial in its original carton until immediately before use, and avoid exposure to direct sunlight or excess heat. Store this medicine out of reach of children and ensure only trained healthcare staff handle preparation and administration.
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