Carplatu 150mg/15ml 1`s

A healthcare professional gives it as an intravenous infusion.

Carplatu 150mg/15ml Ingredients and Usage

Carplatu 150mg/15ml contains carboplatin, a platinum based chemotherapy drug from the alkylating agent class. An alkylating agent is a medicine that damages cancer cell DNA to stop the cells from dividing. Doctors prescribe Carplatu mainly for advanced ovarian carcinoma and small cell lung cancer.

Carplatu 150mg/15ml also treats head and neck, bladder, cervical, endometrial and breast cancers in combination regimens. Oncologists often choose carboplatin over cisplatin for patients with reduced kidney function. A healthcare professional gives Carplatu as an intravenous infusion over at least 15 minutes.

How Does Carplatu 150mg/15ml Work?

Carplatu 150mg/15ml works by damaging the DNA inside cancer cells so they can no longer multiply. After entering the cell, carboplatin undergoes aquation and binds directly to DNA strands. It forms inter strand and intra strand cross links that lock the DNA and block replication.

This DNA damage triggers apoptosis, the natural process of programmed cell death, in the tumour. Carboplatin acts at all phases of the cell cycle, making it a non phase specific agent. The result is halted tumour growth across a range of solid cancers.

Carplatu 150mg/15ml Side Effects

Carplatu 150mg/15ml commonly affects bone marrow and the digestive system. Your medical team will monitor your blood counts closely throughout treatment.

• Myelosuppression, the drop in blood cell production, which is the main dose limiting effect

• Thrombocytopenia, a low platelet count that raises bleeding risk

• Low white cells and anaemia, increasing infection and fatigue risk

• Nausea and vomiting, usually milder than with cisplatin

• Fatigue and general weakness

• Peripheral neuropathy, causing tingling or numbness in hands and feet

• Kidney function changes (nephrotoxicity)

• Hearing changes or ringing in the ears (ototoxicity)

Warnings

• Do not take Carplatu 150mg/15ml if you have a known allergy to carboplatin, cisplatin or other platinum compounds.

• Carboplatin can harm an unborn baby. Women must avoid pregnancy and use effective contraception during treatment.

• Carplatu raises the risk of severe hypersensitivity reactions, which can include rash, breathlessness and a drop in blood pressure.

• This medicine suppresses bone marrow. Your doctor will check platelets and white cells before each cycle.

• Combining Carplatu with other nephrotoxic drugs such as aminoglycoside antibiotics increases kidney damage risk.

• Carboplatin reduces immunity, so avoid live vaccines during treatment.

• Tell your doctor about kidney problems, as the dose depends on your kidney function.

Carplatu 150mg/15ml Storage Conditions

Store Carplatu 150mg/15ml below 30 degrees Celsius in its original carton, protected from direct light. Keep the vial in a dry place and do not freeze the solution. Refrigeration is not required for the unopened vial. A healthcare professional uses the prepared infusion promptly, and the product stays out of the sight and reach of children as a cytotoxic medicine.