Synflex-M 85+500mg Tablets offer a specialized clinical combination for the management of migraine and tension headaches, provided by PakMeds with reliable home delivery.

ManufacturerSearle Pakistan Ltd
Active IngredientsNaproxen Sodium and Domperidone
Medicine Strength85mg/500mg
Number Per Pack20 Tablets
Requires Prescription?Yes
GenericsNSAID and Antiemetic Combination

Synflex-M 85+500mg Tablets Ingredients and Usage

Synflex-M is a unique clinical combination of Naproxen Sodium (500mg) and Domperidone (85mg). This medication is specifically formulated for the treatment of migraine attacks, especially those accompanied by nausea and vomiting. While the Naproxen Sodium addresses the inflammatory pain and throbbing sensation of the migraine, the Domperidone helps control the associated gastric symptoms and improves drug absorption. PakMeds provides this targeted therapy to help migraine sufferers regain control over their day by treating both the pain and the gastrointestinal distress of an attack.

How Does Synflex-M 85+500mg Tablets Work?

This combination works through two distinct mechanisms. Naproxen Sodium inhibits the synthesis of prostaglandins, which are responsible for the neurogenic inflammation and pain signals in the brain during a migraine. Domperidone acts as a dopamine antagonist that increases the motility of the upper gastrointestinal tract. During a migraine, the stomach often slows down (gastric stasis), which can prevent pain medications from being absorbed. By stimulating gastric emptying, Domperidone ensures that the Naproxen is absorbed quickly and efficiently, providing faster relief.

Synflex-M 85+500mg Tablets Side Effects

Possible side effects include dry mouth, headache, and mild gastrointestinal upset. Some patients may report drowsiness or dizziness. Because it contains Domperidone, some individuals might experience transient changes in heart rhythm or breast tenderness due to hormonal shifts.

List of Warnings:

  • Monitor for cardiac side effects, especially in patients with a history of heart rhythm disorders.
  • Avoid use in patients with a known history of prolactinoma or significant hepatic impairment.
  • Take the tablet at the first sign of a migraine attack for maximum clinical efficacy.
  • Consult your doctor if you are taking other medications that prolong the QT interval.

Synflex-M 85+500mg Tablets Storage Conditions

Keep Synflex-M Tablets in a dry place at room temperature, ideally below 25°C. Protect the medicine from direct sunlight and heat. Always maintain the tablets in the original blister packaging to ensure stability and keep them in a safe location away from children.

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