Oxalisol 100mg IV Inj. 1`s

A qualified oncology team administers it as a slow intravenous infusion under close medical supervision.x

Oxalisol 100mg IV Injection Ingredients and Usage

Oxalisol 100mg IV Injection contains oxaliplatin, a diaminocyclohexane platinum compound belonging to the alkylating anticancer drug class. Oncologists prescribe it as adjuvant therapy for stage III colon cancer following surgical removal of the primary tumor.

Oxalisol 100mg IV Injection also treats advanced or metastatic colorectal cancer, typically combined with 5-fluorouracil and leucovorin in FOLFOX or CAPOX regimens. Treatment follows fixed cycles, and a specialist experienced in chemotherapy administration must supervise every infusion.

How Does Oxalisol 100mg IV Injection Work?

Oxaliplatin forms platinum DNA crosslinks between adjacent guanine bases within cancer cell DNA. These crosslinks physically distort the DNA structure and block the enzymes needed for replication and transcription.

By preventing DNA replication, Oxalisol 100mg IV Injection stops actively dividing cancer cells from multiplying and triggers cell death. Unlike cisplatin, oxaliplatin remains active against some cisplatin resistant tumor cell lines, giving it a distinct role in colorectal cancer treatment.

Oxalisol 100mg IV Injection Side Effects

Oxalisol 100mg IV Injection commonly causes nerve related and digestive side effects. Cold triggered nerve symptoms are a distinctive feature of this medicine.

• Peripheral neuropathy, tingling or numbness in hands, feet, and around the mouth, often worsened by cold

• Nausea and vomiting

• Diarrhea

• Fatigue

• Low platelet and white blood cell counts

• Mouth sores

• Throat and jaw tightness during infusion

Warnings

• Oxalisol 100mg IV Injection is contraindicated in patients with known allergy to oxaliplatin or other platinum compounds, since cross reactivity is common.

• Hypersensitivity reactions can occur, most often within the first 20 minutes of infusion; patients should be monitored closely during this period.

• Avoid cold drinks, ice, and cold air exposure during and immediately after infusion, since cold can trigger or worsen acute nerve symptoms including throat tightness.

• Regular blood count monitoring is required, since Oxalisol 100mg IV Injection can cause neutropenia, thrombocytopenia, and anemia.

• Peripheral neuropathy is cumulative with repeated cycles and may become persistent at higher total doses; report worsening numbness or weakness promptly.

• Avoid aluminum containing needles and infusion equipment, since aluminum can degrade the platinum compound.

• Use with caution in pregnancy and breastfeeding, since safety data are limited; discuss risks and benefits with a specialist before starting therapy.

Oxalisol 100mg IV Injection Storage Conditions

Store Oxalisol 100mg IV Injection in a cool, dry place protected from direct light, following the storage temperature stated on the vial label. Keep the vial in its original packaging until immediately before use. Store this medicine out of reach of children and ensure only trained healthcare staff handle preparation and administration.