Hilfo-B 25mg Tabs. 30`s

Doctors prescribe it as a once daily oral tablet to suppress viral replication and protect liver function over the long term.

Hilfo-B 25mg Tablet Ingredients and Usage

Hilfo-B 25mg Tablet contains tenofovir alafenamide, a nucleotide analogue belonging to the antiviral drug class. Doctors prescribe it for chronic hepatitis B virus infection in adults and adolescents aged 12 years or older weighing at least 35 kilograms who have compensated liver disease.

Hilfo-B 25mg Tablet is taken once daily as a long-term maintenance therapy to suppress viral replication and reduce liver inflammation. Regular liver function and viral load monitoring guides the duration of treatment.

How Does Hilfo-B 25mg Tablet Work?

Tenofovir alafenamide is a prodrug that is absorbed and converted inside liver cells into tenofovir diphosphate, its active form. This active metabolite competitively inhibits the hepatitis B virus polymerase, the enzyme the virus needs to replicate its DNA.

By incorporating into the growing viral DNA strand, Hilfo-B 25mg Tablet causes chain termination, stopping the virus from completing replication. Because it delivers the active drug more efficiently into liver cells, it achieves antiviral effect at a much lower dose than older tenofovir formulations.

Hilfo-B 25mg Tablet Side Effects

Hilfo-B 25mg Tablet is generally well tolerated, with side effects usually mild.

• Headache

• Abdominal pain

• Fatigue

• Cough

• Nausea

• Back pain

• Joint pain

Warnings

• Hilfo-B 25mg Tablet carries a boxed warning for severe acute exacerbation of hepatitis B after stopping treatment; patients must never discontinue the medicine without informing their doctor, and liver function should be monitored for several months after stopping.

• The medicine also carries a boxed warning for lactic acidosis and severe hepatomegaly with steatosis, a rare but potentially fatal reaction associated with this drug class.

• Kidney function, including serum creatinine and urine protein, should be checked before starting treatment and periodically thereafter, since tenofovir products can cause new or worsening kidney impairment.

• Avoid combining Hilfo-B 25mg Tablet with other nephrotoxic drugs, including NSAIDs, since this raises the risk of kidney related adverse effects.

• Patients with HIV coinfection who are not on effective HIV treatment should not use Hilfo-B 25mg Tablet alone, since this may increase the risk of HIV drug resistance; all patients should be tested for HIV before starting.

• Drugs that strongly affect P-glycoprotein or breast cancer resistance protein transporters may change how much tenofovir alafenamide is absorbed; inform the doctor of all other medications.

• Discuss risks and benefits with a doctor before use during pregnancy or breastfeeding.

Hilfo-B 25mg Tablet Storage Conditions

Store Hilfo-B 25mg Tablet at room temperature, away from direct sunlight, heat, and moisture. Keep tablets in their original packaging until the dose is due. Store this medicine out of reach of children and dispose of any expired or unused tablets according to local pharmacy guidelines.