ManufacturerVarious Pharmaceutical Companies
Active IngredientsGlycopyrronium Bromide
Medicine Strength0.2mg per ml
FormulationSolution for Intravenous/Intramuscular/Subcutaneous Injection
Requires Prescription?Yes (Hospital Use – Anesthesiologist or Physician prescription required)
GenericsGlycopyrrolate, Glycopyrronium

Glycol P Ingredients and Usage

The active ingredient is Glycopyrronium Bromide, a synthetic quaternary ammonium anticholinergic agent. It is administered parenterally in doses of 0.1-0.2mg, typically 30-60 minutes before anesthesia induction or as needed for secretion control, with dosage adjusted based on clinical indication and patient response.

Glycol P is clinically indicated for:

  • Pre-anesthetic medication to reduce salivary and respiratory secretions
  • Intraoperative and postoperative bradycardia management
  • Peptic ulcer disease and gastrointestinal hypermotility
  • Chronic drooling in neurological disorders
  • Reversal of neuromuscular blockade in combination with neostigmine

How Does Glycol P Work?

Glycol P provides anticholinergic effects through muscarinic receptor blockade:

  1. Muscarinic Antagonism: Competitively blocks acetylcholine at muscarinic receptors
  2. Secretion Reduction: Inhibits glandular secretions including salivary and bronchial
  3. GI Motility Reduction: Decreases gastrointestinal motility and gastric acid secretion
  4. Cardiac Effects: Increases heart rate by blocking vagal stimulation

Glycol P Side Effects and Warnings

Common side effects include dry mouth, blurred vision, urinary retention, constipation, and tachycardia. Most adverse effects are related to its anticholinergic properties.

Serious Considerations

  1. Glaucoma Risk: May precipitate acute angle-closure glaucoma
  2. Urinary Retention: Can cause urinary retention, especially in elderly men with BPH
  3. Cardiac Conditions: Use with caution in patients with tachycardia, heart failure, or coronary artery disease
  4. GI Obstruction: Contraindicated in patients with mechanical intestinal obstruction
  5. Myasthenia Gravis: May exacerbate symptoms of myasthenia gravis

Glycol P Storage Conditions

Glycol P Injection requires proper storage conditions:

  • Store at controlled room temperature 15-30°C
  • Protect from light and freezing
  • Keep in original container
  • Use only if solution is clear and colorless
  • Discard unused portions appropriately
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