Folinis 75IU Inj. 1`s

Manufacturer
Active Ingredients	Menotropin (Human Menopausal Gonadotropin)
Medicine Strength	75 International Units per vial
Formulation	Powder for Solution for Intramuscular/Subcutaneous Injection
Requires Prescription?	Yes (Fertility Specialist prescription required)
Generics	Menotropin, hMG

Folinis Menotropin Ingredients and Usage

The active ingredient is Menotropin, extracted from the urine of postmenopausal women, containing both FSH and LH activity. It is administered by intramuscular or subcutaneous injection daily, with dosage individually adjusted based on ovarian response monitored by ultrasound and estrogen levels. Folinis Menotropin is clinically indicated for:

• Ovulation induction in anovulatory women
• Controlled ovarian hyperstimulation in assisted reproductive technologies (ART)
• Stimulation of multiple follicle development in IVF cycles
• Hypogonadotropic hypogonadism in both men and women

How Does Folinis Menotropin Work?

Folinis Menotropin stimulates ovarian function through gonadotropin activity:

1. Follicle Stimulation: FSH activity promotes growth and development of ovarian follicles
2. Steroidogenesis: LH activity stimulates estrogen production by developing follicles
3. Ovulation Induction: Supports final follicular maturation and ovulation when combined with hCG
4. Multiple Follicle Development: Stimulates development of multiple follicles for ART procedures

Folinis Menotropin Side Effects and Warnings

Common side effects include injection site reactions, ovarian enlargement, abdominal pain, bloating, headache, and mood swings. Most effects are mild and related to the desired ovarian stimulation.

Serious Considerations

1. Ovarian Hyperstimulation Syndrome (OHSS): May cause severe OHSS requiring medical intervention
2. Multiple Pregnancy: Significantly increases risk of multiple gestation pregnancies
3. Ovarian Torsion: Enlarged ovaries are at risk of torsion - a surgical emergency
4. Ectopic Pregnancy: Increased risk of ectopic and heterotopic pregnancies
5. Thromboembolic Events: Higher risk of arterial and venous thromboembolism

Folinis Menotropin Storage Conditions

Folinis Menotropin Injection requires strict storage conditions:

• Store unreconstituted powder at 2°C to 8°C
• Protect from light and freezing
• Use reconstituted solution immediately
• Do not freeze reconstituted solution
• Keep out of reach of children