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Fcm (Ferric Carboxymaltose) Iv Injection 500mg/10ml
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Overview
| Manufacturer | Various Pharmaceutical Companies |
| Active Ingredients | Ferric Carboxymaltose |
| Medicine Strength | 500mg per 10ml vial (50mg elemental iron per ml) |
| Formulation | Solution for Intravenous Injection/Infusion |
| Requires Prescription? | Yes (Hospital/Clinic Administration - Physician prescription required) |
| Generics | Ferric Carboxymaltose |
FCM Ingredients and Usage
The active ingredient is Ferric Carboxymaltose, a stable complex of ferric iron and carboxymaltose. It is administered as a single intravenous dose up to 1000mg, either as a slow injection or diluted infusion, under medical supervision.
FCM is clinically indicated for:
- Iron deficiency anemia when oral iron is ineffective or poorly tolerated
- Iron deficiency in chronic kidney disease patients
- Postpartum iron deficiency anemia
- Preoperative anemia management
- Inflammatory bowel disease with iron deficiency
How Does FCM Work?
FCM provides rapid iron repletion through controlled iron release:
- Targeted Iron Delivery: Provides iron in a stable complex that minimizes free iron toxicity
- Macrophage Uptake: Taken up by reticuloendothelial system macrophages
- Controlled Release: Slowly releases iron to transferrin for hemoglobin synthesis
- Rapid Hemoglobin Response: Significantly increases hemoglobin levels within 1-2 weeks
FCM Side Effects and Warnings
Common side effects include nausea, headache, dizziness, hypertension, and injection site reactions. Hypophosphatemia may occur but is usually transient.
Serious Considerations
- Hypersensitivity Reactions: May cause anaphylaxis - administer in monitored settings
- Hypotension: Can cause transient hypotension during or after administration
- Hypophosphatemia: May cause significant phosphate lowering requiring monitoring
- Oxidative Stress: Free iron may potentially increase oxidative stress
- Overload Risk: Avoid in patients with iron overload syndromes
FCM Storage Conditions
FCM Injection requires proper storage conditions:
- Store below 25°C in original carton
- Protect from light and freezing
- Use immediately after opening
- Do not use if solution is discolored or contains particles
- Keep out of reach of children
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