
Epival 500mg (100 Tablets)
Epival 500mg Tablets (10x10s) is a high-quality pharmaceutical product used for the treatment of various types of epilepsy and the management of manic episodes in bipolar disorder, available for home delivery at PakMeds.
| Manufacturer | Abbott Laboratories (Pakistan) Ltd. |
| Active Ingredients | Sodium Valproate |
| Medicine Strength | 500 mg |
| Number Per Pack | 100 Tablets |
| Requires Prescription? | Yes |
| Generics | Sodium Valproate |
Epival 500mg Tablets Ingredients and Usage
Epival 500mg Tablets contain Sodium Valproate, a widely used antiepileptic medication in Pakistan. It is indicated for the treatment of various forms of epilepsy, including generalized, partial, and other specific seizure types. Beyond epilepsy, it is also highly effective in managing the manic episodes associated with bipolar disorder, helping to stabilize mood and prevent extreme emotional shifts.
In clinical practice, Epival is also frequently prescribed as a preventive treatment for migraine headaches in adults who experience frequent or severe attacks. By controlling the electrical activity in the brain, it helps patients lead more stable and predictable lives. PakMeds provides authentic Epival to ensure consistent therapeutic support for patients managing these chronic neurological and psychiatric conditions.
The 500 mg strength is often used for maintenance therapy in adults. It is essential that this medication is used under strict medical supervision to ensure the dosage is optimized for the patient’s specific needs and to monitor for clinical response throughout the treatment period.
How Does Epival 500mg Tablets Work?
Sodium Valproate works by increasing the levels of Gamma-Aminobutyric Acid (GABA) in the brain. GABA is an inhibitory neurotransmitter that helps to calm down the nervous system and prevent over-excitation of nerve cells. By enhancing GABAergic activity, Epival reduces the likelihood of the abnormal electrical discharges that trigger seizures.
Furthermore, the medication may also act on voltage-gated sodium and calcium channels, further stabilizing the neuronal membranes. This multi-pathway action makes it a broad-spectrum antiepileptic drug, effective against many different seizure patterns. In mood stabilization, it helps regulate the firing of neurons involved in emotional regulation, preventing the “highs” of mania.
The medication is absorbed steadily into the bloodstream, where it maintains therapeutic levels required to suppress seizure activity 24 hours a day. Consistent dosing is key to its success in preventing breakthrough seizures and maintaining mood stability.
Epival 500mg Tablets Side Effects
Common side effects of Epival 500mg include nausea, tremors, and drowsiness. Some patients may notice weight gain, an increase in appetite, or temporary hair loss. These effects are often dose-dependent and may diminish as the body adjusts to the medication. Gastrointestinal upset can often be minimized by taking the tablets with food.
More serious but rare side effects include liver toxicity and inflammation of the pancreas (pancreatitis). If you experience severe abdominal pain, persistent vomiting, or yellowing of the skin/eyes, seek medical help immediately. PakMeds recommends regular blood tests to monitor liver function and platelet counts as directed by your physician.
List of Warnings:
- Do not stop taking this medication suddenly, as it may trigger severe or continuous seizures.
- Extremely high risk of birth defects; must not be used in pregnancy unless no other treatment is available.
- Women of childbearing age must use highly effective contraception while on this medication.
- Inform your doctor if you have a history of liver disease or urea cycle disorders.
- Monitor for any changes in mood, such as increased depression or suicidal thoughts.
Epival 500mg Tablets Storage Conditions
Store in a cool, dry place at room temperature below 30°C. Protect the tablets from direct light and moisture by keeping them in the original blister pack. Always keep this and all other medications out of the reach and sight of children.
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