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Eltrom 25mg Tablets 28S
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Overview
| Manufacturer | Getz Pharma Pakistan |
| Active Ingredients | Eltrombopag Olamine |
| Medicine Strength | 25mg per Tablet |
| Formulation | Film-Coated Tablets |
| Requires Prescription? | Yes (Hematologist prescription required) |
| Generics | Eltrombopag |
Eltrom Ingredients and Usage
The active ingredient is Eltrombopag Olamine, identical to Revolade formulation. The 25mg tablet is taken once daily on an empty stomach at least 1 hour before or 2 hours after food.
Eltrom is clinically indicated for:
- Chronic immune thrombocytopenia in adult patients
- Patients who have insufficient response to corticosteroids
- Thrombocytopenia in chronic hepatitis C patients
- Severe aplastic anemia treatment
How Does Eltrom Work?
Eltrom provides targeted platelet stimulation through specific mechanisms:
- TPO Receptor Activation: Binds to human thrombopoietin receptor
- Megakaryocyte Growth: Stimulates bone marrow megakaryocyte proliferation
- Platelet Production: Increases circulating platelet counts
- JAK-STAT Pathway: Activates intracellular signaling cascades
Eltrom Side Effects and Warnings
Common side effects include headache, nausea, diarrhea, and elevated liver enzymes. Most reactions are mild to moderate and manageable.
Serious Considerations
- Hepatotoxicity: Regular liver function monitoring essential
- Bone Marrow Fibrosis: Risk of increased reticulin formation
- Thrombotic Risk: Blood clot risk with elevated platelet counts
- Cataract Development: Regular ophthalmological examinations needed
- Drug Interactions: Chelates with polyvalent cations affecting absorption
Eltrom Storage Conditions
Eltrom Tablets require proper storage conditions:
- Store at room temperature below 30°C
- Keep in original packaging protected from moisture
- Protect from light and excessive heat
- Keep out of reach of children
- Do not use after expiration date
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