Elbonix 25mg Tablets 28s (Eltrombopag)

Manufacturer	Novartis Pharma Pakistan
Active Ingredients	Eltrombopag Olamine
Medicine Strength	25mg per Tablet
Formulation	Film-Coated Tablets
Requires Prescription?	Yes (Hematologist prescription required)
Generics	Eltrombopag

Elbonix Ingredients and Usage

The active ingredient is Eltrombopag Olamine, an oral thrombopoietin receptor agonist. The 25mg tablet is taken once daily on an empty stomach at least 1 hour before or 2 hours after food.Elbonix is clinically indicated for:

• Chronic immune thrombocytopenia in refractory patients

• Thrombocytopenia in chronic hepatitis C patients

• Severe aplastic anemia treatment

• Patients who are splenectomized or non-splenectomized

How Does Elbonix Work?

Elbonix stimulates platelet production through thrombopoietin receptor activation:

1. TPO Receptor Binding: Activates human thrombopoietin receptor

2. Megakaryocyte Stimulation: Promotes proliferation and differentiation

3. Platelet Production: Increases platelet counts in circulation

4. Selective Action: Works independently of endogenous thrombopoietin

Elbonix Side Effects and Warnings

Common side effects include headache, nausea, diarrhea, and elevated liver enzymes. Most effects are manageable with dose adjustment.

Serious Considerations

1. Hepatotoxicity: Regular liver function monitoring required

2. Bone Marrow Fibrosis: Risk of increased reticulin formation

3. Thrombotic Risk: Increased risk of blood clots with high platelet counts

4. Cataract Development: Regular ophthalmological examinations needed

5. Drug Interactions: Chelates with polyvalent cations affecting absorption

Elbonix Storage Conditions

Elbonix Tablets require proper storage conditions:

• Store at room temperature below 30°C

• Keep in original packaging protected from moisture

• Protect from light and excessive heat

• Keep out of reach of children

• Do not use after expiration date