Duphalac Syrup (120ml) is a high-quality pharmaceutical product used for the treatment of chronic constipation and hepatic encephalopathy, available for home delivery at PakMeds.

ManufacturerAbbott Laboratories
Active IngredientsLactulose
Medicine Strength3.35 g per 5 ml
Number Per Pack120 ml Bottle
Requires Prescription?No (OTC)
GenericsLactulose

Duphalac Syrup Ingredients and Usage

Duphalac Syrup contains Lactulose, a synthetic sugar used as an osmotic laxative. In Pakistan, Duphalac is one of the most widely prescribed treatments for chronic constipation. It is uniquely safe for use in all age groups, including infants, children, the elderly, and pregnant women.

It is also a critical medication for the management of hepatic encephalopathy, a brain dysfunction caused by severe liver disease. By helping the body eliminate toxins, it protects neurological health in patients with liver failure. PakMeds provides Duphalac Syrup to support both digestive regularity and critical liver care.

The clear, sweet-tasting syrup is easy to administer and is particularly useful for those who require a gentle approach to constipation that does not cause sudden urgency or painful cramping.

How Does Duphalac Syrup Work?

Lactulose is a synthetic disaccharide that is not absorbed in the small intestine. When it reaches the colon, it is broken down by the natural colonic bacteria into low-molecular-weight organic acids, such as lactic and acetic acid.

These acids increase the osmotic pressure in the bowel, which draws water into the colon. This process softens the stool and increases its volume, which in turn stimulates the natural wave-like movements (peristalsis) of the intestine. In liver disease, this acidification helps trap ammonia in the gut, preventing it from entering the bloodstream and reaching the brain.

By effectively managing the fluid balance in the colon, Duphalac ensures a gradual and natural bowel movement. Because it works through the gut’s own bacteria, it helps restore a healthy intestinal environment over time.

Duphalac Syrup Side Effects

During the first few days of treatment, mild side effects like flatulence and abdominal bloating are common as the gut bacteria adapt. These symptoms usually disappear with continued use. At higher doses, diarrhea and abdominal pain may occur.

If taken in excessive quantities for a long period, it can lead to an electrolyte imbalance. Some patients may experience mild nausea. PakMeds recommends starting with a lower dose and gradually increasing it as needed to minimize initial gas production and ensure the best comfort.

List of Warnings:

  • Contraindicated in patients with galactosemia or total bowel obstruction.
  • Use with caution in diabetic patients due to the sugar content, although absorption is minimal.
  • Ensure you drink plenty of water (6-8 glasses a day) while taking osmotic laxatives.
  • If constipation persists after several days of treatment, consult a healthcare professional.
  • Do not use for more than two weeks without medical supervision if symptoms are recurring.

Duphalac Syrup Storage Conditions

Store at room temperature (15-25°C). Avoid freezing, as this can cause the syrup to crystallize. If crystals form, warming the bottle gently will dissolve them. Keep the bottle tightly closed and away from children.

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