Cova-H Tab 80Mg+12.5Mg Tp 14'S

It pairs an angiotensin receptor blocker with a thiazide diuretic for stronger blood pressure control.

Cova-H Tab 80mg+12.5mg 14's Ingredients and Usage

Cova-H Tab 80mg+12.5mg 14's combines Valsartan, an angiotensin II receptor blocker (ARB), with Hydrochlorothiazide, a thiazide diuretic. Doctors prescribe this fixed dose combination for hypertension that monotherapy alone does not control adequately. It also has a role in managing heart failure and post myocardial infarction care in appropriate patients.

The 80mg/12.5mg strength typically serves as a starting dose for combination therapy or a step up from Valsartan alone. Each active ingredient targets a different pathway, so together they lower blood pressure more effectively than either drug used on its own.

How Does Cova-H Tab 80mg+12.5mg 14's Work?

Valsartan blocks the AT1 receptor, the site where angiotensin II normally binds to narrow blood vessels and raise blood pressure. By blocking this receptor, Valsartan relaxes vascular smooth muscle and reduces cardiac venous return.

Hydrochlorothiazide inhibits the sodium chloride symporter in the distal renal tubule, so the kidneys excrete more sodium and water. This lowers circulating blood volume, which reduces arterial pressure. The diuretic action also triggers a rise in renin and aldosterone, and Valsartan blocks this compensatory response through the renin angiotensin aldosterone system (RAAS).

Cova-H Tab 80mg+12.5mg 14's Side Effects

Most patients tolerate Cova-H Tab 80mg+12.5mg 14's well, though some experience mild reactions as the body adjusts to the medication.

• Dizziness or lightheadedness

• Dry cough

• Increased blood urea nitrogen

• Hyperkalemia (raised blood potassium)

• Headache

• Increased urination

Warnings

• Do not take Cova-H Tab 80mg+12.5mg 14's if you have a known hypersensitivity to Valsartan, Hydrochlorothiazide, or sulfa drugs.

• Avoid combining this medicine with aliskiren if you have diabetes or kidney impairment, since this raises the risk of hyperkalemia and low blood pressure.

• Valsartan carries a boxed warning for pregnancy; drugs acting on the renin angiotensin system can cause fetal injury and death in the second and third trimesters.

• Use with caution in patients with renal artery stenosis, liver disease, or volume depletion from high dose diuretics, a salt restricted diet, vomiting, or diarrhea.

• Tell your doctor about all other medications, since Valsartan and Hydrochlorothiazide interact with many drugs, including other blood pressure medicines and NSAIDs.

Cova-H Tab 80mg+12.5mg 14's Storage Conditions

Store Cova-H Tab 80mg+12.5mg 14's at a controlled room temperature below 30°C, away from direct sunlight and moisture. Keep the blister pack tightly sealed until use to protect the tablets from humidity. Keep this medicine out of reach and sight of children, and do not use it past its printed expiry date.