Colofac 135 mg Tablets (30s) is a high-quality pharmaceutical product used for the management of irritable bowel syndrome (IBS) and intestinal spasms, available for home delivery at PakMeds.

Colofac 135 mg Tablets Ingredients and Usage

Colofac 135 mg Tablets contain Mebeverine Hydrochloride, a specialized musculotropic antispasmodic medication. In Pakistan, Colofac is a leading choice for the symptomatic relief of irritable bowel syndrome (IBS) and other conditions related to gastrointestinal tract spasms.

These conditions often manifest as abdominal pain and cramps, persistent diarrhea (sometimes alternating with constipation), and flatulence. Colofac is particularly valued because it helps manage these symptoms without affecting the normal motility of the gut, allowing the digestive process to proceed naturally.

By effectively targeting the smooth muscle of the intestine, it provides relief from the distress of chronic bowel sensitivity. PakMeds offers Colofac to help patients regain control over their digestive comfort and improve their daily quality of life.

How Does Colofac 135 mg Tablets Work?

The active ingredient, Mebeverine, acts directly on the smooth muscles of the gastrointestinal tract, especially the colon. Unlike other antispasmodics, it does not work through the autonomic nervous system, which means it avoids common “anticholinergic” side effects like dry mouth or blurred vision.

It works by inhibiting the influx of sodium ions into the smooth muscle cells and restricting the replenishment of calcium from intracellular stores. This stabilization of the muscle cell membrane prevents the over-activity and spasms that cause abdominal pain and cramping.

Because it acts specifically on the gut wall, it helps to normalize bowel function without causing the systemic side effects associated with many other relaxants. This focused action makes it suitable for long-term management of recurring digestive spasms.

Colofac 135 mg Tablets Side Effects

Colofac is generally well-tolerated by most patients. However, rare side effects may include localized skin reactions such as hives, swelling of the face, or a mild rash. Some individuals may experience mild dizziness or indigestion during the first few days of use.

In extremely rare cases, a severe allergic reaction known as angioedema can occur. If you develop any significant swelling of the lips or throat, discontinue use and seek medical help immediately. PakMeds recommends monitoring your response and consulting a pharmacist if you have concerns about sensitivity.

List of Warnings:

• Do not use if you have a known hypersensitivity to Mebeverine Hydrochloride.
• Avoid use if you have a condition called paralytic ileus (complete lack of bowel movement).
• Consult your doctor if you notice blood in your stools or have a fever accompanying gut pain.
• Not recommended for use during pregnancy or breastfeeding unless specifically advised by a specialist.
• Ensure you are not taking other antispasmodics without medical supervision.

Colofac 135 mg Tablets Storage Conditions

Store in a cool, dry place at room temperature below 30°C. Protect the tablets from direct light and moisture by keeping them in the original blister pack. Keep all medications safely out of the reach and sight of children.