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Cefcom 250 mg Inj
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Overview
| Manufacturer | CCL Pharmaceuticals Pakistan |
| Active Ingredients | Cefoperazone Sodium and Sulbactam Sodium |
| Medicine Strength | 250mg per vial (125mg Cefoperazone + 125mg Sulbactam) |
| Formulation | Powder for Solution for Intravenous/Intramuscular Injection |
| Requires Prescription? | Yes (Hospital/Specialist use only) |
| Generics | Cefoperazone/Sulbactam |
Cefcom Ingredients and Usage
The active ingredients are Cefoperazone Sodium and Sulbactam Sodium in 1:1 ratio. The 250mg strength is suitable for pediatric dosing and less severe infections.
Cefcom 250mg is clinically indicated for:
- Moderate respiratory tract infections
- Uncomplicated skin and soft tissue infections
- Urinary tract infections
- Pediatric bacterial infections
How Does Cefcom Work?
Cefcom 250mg provides targeted antibacterial action:
- Bacterial Cell Wall Disruption: Inhibits peptidoglycan synthesis
- Enzyme Protection: Sulbactam protects against beta-lactamase degradation
- Broad Coverage: Effective against common pathogens
- Flexible Administration: Suitable for both IV and IM routes
Cefcom Side Effects and Warnings
Common side effects include mild gastrointestinal upset, injection site pain, and transient rash. Most reactions resolve without intervention.
Serious Considerations
- Allergy Cross-reactivity: Contraindicated in patients with cephalosporin allergy
- Pediatric Dosing: Requires weight-based calculation for children
- Alcohol Interaction: Disulfiram-like reaction with alcohol consumption
- Renal Function: Monitor in patients with pre-existing kidney disease
- Bleeding Tendency: May affect vitamin K-dependent clotting factors
Cefcom Storage Conditions
Cefcom 250mg requires proper storage handling:
- Store below 25°C in dry place
- Protect from light and moisture
- Use reconstituted solution within 24 hours if refrigerated
- Discard unused portions properly
- Inspect for discoloration before use
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