Cardioplegia Inj 200 mg
Cardioplegia Injection is a specialized solution used during cardiac surgery to induce rapid cardiac arrest and protect the myocardium. Buy Cardioplegia Injection online at PakMeds for cardiac surgery support.
| Manufacturer | Atco Laboratories Limited |
| Active Ingredients | Potassium Chloride with electrolytes and cardioprotective agents |
| Medicine Strength | Various formulations (typically 20-30 mEq/L Potassium) |
| Formulation | Sterile Solution for Intracardiac Infusion |
| Requires Prescription? | Yes (Cardiac Surgery use only) |
| Generics | Cardioplegia Solution |
Cardioplegia Ingredients and Usage
The solution contains Potassium Chloride as the primary arresting agent along with magnesium, calcium, buffers, and metabolic substrates. It is administered directly into the coronary arteries during cardiac surgery.
Cardioplegia is clinically indicated for:
- Myocardial protection during coronary artery bypass surgery
- Cardiac valve replacement and repair procedures
- Congenital heart defect corrections
- Aortic root and other complex cardiac surgeries
How Does Cardioplegia Work?
Cardioplegia induces controlled cardiac arrest through multiple protective mechanisms:
- Cardiac Arrest Induction: High potassium concentration depolarizes myocardial cells, stopping electrical activity
- Myocardial Protection: Reduces metabolic demand by 90% during arrest period
- Ischemic Protection: Contains substrates that maintain cellular integrity during ischemia
- Reperfusion Protection: Buffers and antioxidants minimize reperfusion injury
Cardioplegia Side Effects and Warnings
Potential complications include incomplete myocardial protection, electrolyte imbalances, and reperfusion injuries. Proper administration technique minimizes these risks.
Serious Considerations
- Hyperkalemia Risk: High potassium content requires careful monitoring to prevent systemic hyperkalemia
- Myocardial Stunning: Inadequate protection may lead to postoperative myocardial dysfunction
- Administration Technique: Requires precise coronary ostia cannulation by experienced cardiac surgeons
- Temperature Management: Both cold and warm cardioplegia techniques require strict temperature control
- Composition Variation: Different formulations (crystalloid, blood) require specific protocols
Cardioplegia Storage Conditions
Cardioplegia Injection requires specialized storage:
- Store at controlled room temperature unless specified for cold storage
- Protect from freezing and excessive heat
- Use immediately after preparation or according to manufacturer guidelines
- Inspect for clarity and absence of particles before use
- Follow strict aseptic techniques during preparation
