Amorin 50 mg (100 Tablets)
Amorin 50mg Tablet contains azathioprine, an immunosuppressant used to prevent organ transplant rejection and manage autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease. Buy Amorin 50mg Tablet, pack of 100, at PakMeds with a valid prescription for genuine Mass Pharma stock.
Overview
Doctors prescribe it as a daily tablet under close blood count monitoring.
Manufacturer | Mass Pharma (Pvt) Ltd |
|---|---|
Active Ingredient(s) | Azathioprine |
Strength | 50mg |
Pack Size | 100 tablets |
Prescription Required | Yes |
Generic Name(s) | Azathioprine |
Amorin 50mg Tablet Ingredients and Usage
Amorin 50mg Tablet contains azathioprine, a purine analogue belonging to the immunosuppressant drug class. Doctors prescribe it to prevent rejection following kidney, liver, heart, lung, or pancreas transplantation, helping the body accept the transplanted organ.
Amorin 50mg Tablet also treats severe autoimmune conditions, including rheumatoid arthritis, inflammatory bowel disease, lupus, and certain inflammatory diseases of the skin, liver, and blood vessels. Treatment is guided by a specialist and requires ongoing blood monitoring throughout its use.
How Does Amorin 50mg Tablet Work?
Azathioprine is metabolized into active thiopurine compounds that get incorporated into DNA within rapidly dividing cells, including the immune cells responsible for organ rejection and autoimmune inflammation. This disrupts normal DNA synthesis in these cells.
By interfering with DNA synthesis, Amorin 50mg Tablet reduces the activity and proliferation of immune cells that would otherwise attack a transplanted organ or the body's own healthy tissue. This suppression of the immune response is the basis for its use in both transplantation and autoimmune disease.
Amorin 50mg Tablet Side Effects
Amorin 50mg Tablet commonly causes digestive and blood count related side effects, particularly in the first few months of treatment.
Nausea and vomiting
Low white blood cell count
Increased susceptibility to infection
Fatigue
Muscle and joint pain
Hair thinning
Skin sensitivity to sunlight
Warnings
Long-term use of Amorin 50mg Tablet is associated with an increased risk of lymphoma and other malignancies, particularly skin cancer; regular skin checks and sun protection are recommended.
Patients with low or absent thiopurine methyltransferase or NUDT15 enzyme activity are at risk of severe, life-threatening bone marrow suppression at usual doses; enzyme testing may be considered, especially if severe myelosuppression occurs.
Amorin 50mg Tablet increases the risk of serious bacterial, viral, fungal, and opportunistic infections, including reactivation of latent infections; report fever or signs of infection promptly.
Regular complete blood counts are required throughout treatment to monitor for dangerous drops in white blood cells, red blood cells, or platelets.
Avoid combining Amorin 50mg Tablet with allopurinol or febuxostat unless the azathioprine dose is significantly reduced, since these drugs increase its toxicity.
Amorin 50mg Tablet is not recommended during pregnancy, since it can cause fetal harm; discuss family planning with a doctor before starting treatment.
Avoid live vaccines during treatment, since the weakened immune response increases the risk of infection from the vaccine itself.
Amorin 50mg Tablet Storage Conditions
Store Amorin 50mg Tablet at room temperature, away from direct sunlight and moisture. Keep tablets in their original packaging until the dose is due. Store this medicine out of reach of children and pets, and dispose of any expired or unused tablets according to local pharmacy guidelines.
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