Gastrografin Ingredients and Usage

The active ingredient is Meglumine Diatrizoate, an ionic, high-osmolar contrast medium containing 37% organically bound iodine. It is administered orally or rectally in doses determined by the specific diagnostic procedure and patient factors.

Gastografin is clinically indicated for:

• Gastrointestinal tract radiography (upper GI series, small bowel follow-through)
• Contrast enema for colonic visualization
• Fistula and sinus tract localization
• Post-operative leak detection in gastrointestinal surgery
• Esophageal and gastric emptying studies

How Does Gastografin Work?

Gastografin provides radiographic contrast through iodine absorption properties:

1. X-ray Attenuation: Iodine atoms absorb X-rays creating contrast against surrounding tissues
2. Lumen Opacification: Opacifies the gastrointestinal lumen for clear visualization
3. Anatomical Definition: Outlines the contours and mucosal patterns of GI organs
4. Pathology Detection: Helps identify strictures, obstructions, and pathological changes

Gastrografin Side Effects and Warnings

Common side effects include nausea, vomiting, diarrhea, abdominal cramping, and taste disturbances. Most effects are mild and transient.

Serious Considerations

1. Aspiration Pneumonitis: Can cause severe pulmonary edema if aspirated
2. Dehydration Risk: Hyperosmolar solution may cause significant fluid shifts
3. Iodine Allergy: Contraindicated in patients with known iodine hypersensitivity
4. Thyroid Interference: May interfere with thyroid function tests for weeks
5. Renal Impairment: Use with caution in patients with renal dysfunction

Gastrografin Storage Conditions

Gastografin Liquid requires proper storage conditions:

• Store below 25°C in original container
• Protect from light and freezing
• Keep bottle tightly closed
• Use before expiration date
• Discard any unused portion after opening