Flurocort Ingredients and Usage

The active ingredient is Fludrocortisone Acetate, a synthetic corticosteroid with potent mineralocorticoid and moderate glucocorticoid activity. The 0.1mg tablet is typically taken once daily, often in combination with hydrocortisone for complete adrenal replacement therapy.

Flurocort is clinically indicated for:

• Primary adrenal insufficiency (Addison’s disease)
• Salt-losing adrenogenital syndrome
• Orthostatic hypotension management
• Adrenal crisis prevention in adrenal insufficiency

How Does Flurocort Work?

Flurocort provides mineralocorticoid replacement through renal electrolyte regulation:

1. Sodium Retention: Promotes sodium reabsorption in renal distal tubules
2. Potassium Excretion: Increases potassium excretion through renal mechanisms
3. Blood Pressure Maintenance: Supports blood pressure through fluid volume regulation
4. Mineralocorticoid Replacement: Replaces deficient endogenous mineralocorticoids

Flurocort Side Effects and Warnings

Common side effects include hypertension, fluid retention, hypokalemia, headache, and increased susceptibility to infections. Most effects are dose-dependent and manageable with proper monitoring.

Serious Considerations

1. Hypertension Risk: May cause significant hypertension requiring dose adjustment
2. Hypokalemia: Can cause dangerous potassium depletion – monitor electrolytes regularly
3. Fluid Overload: May precipitate congestive heart failure in susceptible patients
4. Adrenal Suppression: Chronic use suppresses hypothalamic-pituitary-adrenal axis
5. Infection Risk: Increases susceptibility to infections and may mask infection signs

Flurocort Storage Conditions

Flurocort Tablets require proper storage conditions:

• Store below 25°C in original packaging
• Protect from moisture and light
• Keep blister strips sealed until use
• Keep out of reach of children
• Do not use after expiration date