Epinor Ingredients and Usage

The active ingredient is Noradrenaline Acid Tartrate, a potent catecholamine vasopressor. It is administered as a continuous intravenous infusion after dilution, with dosage titrated to maintain target blood pressure.

Epinor is clinically indicated for:

• Acute hypotension in shock states (septic, cardiogenic, neurogenic)
• Blood pressure control in perioperative settings
• Emergency treatment of severe hypotension unresponsive to fluid resuscitation
• Life-threatening low blood pressure conditions

How Does Epinor Work?

Epinor provides rapid vasopressor action through adrenergic receptor stimulation:

1. Alpha-1 Receptor Agonism: Causes potent vasoconstriction of peripheral vessels
2. Blood Pressure Elevation: Increases systemic vascular resistance and mean arterial pressure
3. Beta-1 Receptor Stimulation: Has moderate inotropic and chronotropic cardiac effects
4. Coronary Blood Flow: May increase coronary artery blood flow

Epinor Side Effects and Warnings

Common side effects include anxiety, headache, tremor, palpitations, and bradycardia. Most effects are dose-dependent and managed by infusion rate adjustment.

Serious Considerations

1. Extravasation Risk: May cause severe tissue necrosis – administer through central line
2. Cardiac Arrhythmias: May precipitate serious ventricular arrhythmias
3. Hypertensive Crisis: Can cause severe hypertension if overdosed
4. Ischemic Injury: May reduce organ perfusion despite increased blood pressure
5. Drug Interactions: MAOIs and TCAs can potentiate pressor effects significantly

Epinor Storage Conditions

Epinor Injection requires careful storage and handling:

• Store below 25°C protected from light
• Keep ampoules in original carton until use
• Protect from freezing
• Use immediately after dilution
• Discard any unused portion