ManufacturerVarious Pharmaceutical Companies
Active IngredientsEtanercept
Medicine Strength25mg per vial/prefilled syringe
FormulationPowder for Solution or Prefilled Syringe for Subcutaneous Injection
Requires Prescription?Yes (Rheumatologist or Dermatologist prescription)
GenericsEtanercept

Enercept Ingredients and Usage

The active ingredient is Etanercept, a recombinant human TNF receptor protein. It is typically administered as a subcutaneous injection once or twice weekly, as directed by a healthcare provider.

Enercept is clinically indicated for:

  • Moderate to severe Rheumatoid Arthritis
  • Psoriatic Arthritis
  • Ankylosing Spondylitis
  • Plaque Psoriasis in adults

How Does Enercept Work?

Enercept provides targeted immunomodulation through TNF-alpha inhibition:

  1. TNF-Alpha Binding: Acts as a soluble TNF receptor that binds to TNF-alpha
  2. Inflammation Reduction: Inhibits the inflammatory cascade driven by TNF-alpha
  3. Joint Protection: Reduces joint inflammation and prevents structural damage
  4. Immune Modulation: Modulates the immune response in autoimmune conditions

Enercept Side Effects and Warnings

Common side effects include injection site reactions, upper respiratory infections, headache, and dizziness. Most side effects are mild to moderate.

Serious Considerations

  1. Serious Infections: Increased risk of tuberculosis, invasive fungal and bacterial infections
  2. Malignancy Risk: Higher incidence of lymphoma and other cancers
  3. Heart Failure: May worsen congestive heart failure
  4. Neurological Events: Rare cases of demyelinating disorders reported
  5. Hematologic Events: Pancytopenia and aplastic anemia reported

Enercept Storage Conditions

Enercept Injection requires specific storage conditions:

  • Store at 2°C to 8°C in refrigerator
  • Do not freeze – protect from light
  • Keep in original carton until use
  • Do not shake the solution
  • Use within 14 days if refrigerated after reconstitution
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