Dorcom Ingredients and Usage

The active ingredient is Midazolam, a water-soluble benzodiazepine with rapid onset. The 5mg/mL solution is administered intravenously or intramuscularly for sedation.

Dorcom is clinically indicated for:

• Procedural sedation for minor surgeries
• Preoperative sedation and anxiety relief
• Induction of general anesthesia
• Sedation in intensive care units

How Does Dorcom Work?

Dorcom provides sedation and amnesia through GABA receptor enhancement:

1. GABA Receptor Potentiation: Enhances GABAergic neurotransmission
2. CNS Depression: Produces dose-dependent central nervous system depression
3. Anterograde Amnesia: Prevents memory formation during procedures
4. Rapid Metabolism: Short duration due to rapid hepatic metabolism

Dorcom Side Effects and Warnings

Common side effects include respiratory depression, hypotension, and paradoxical reactions. Most effects are dose-related and reversible.

Serious Considerations

1. Respiratory Depression: Requires continuous monitoring and resuscitation equipment
2. Elderly Patients: Reduced dose needed due to increased sensitivity
3. Drug Interactions: Potentiates effects of other CNS depressants
4. Flumazenil Availability: Benzodiazepine antagonist must be readily available
5. Hepatic Impairment: Dose reduction required in liver dysfunction

Dorcom Storage Conditions

Dorcom Injection requires proper storage handling:

• Store at room temperature below 25°C
• Protect from light and freezing
• Use opened ampoules immediately
• Discard if solution appears discolored or contains particles
• Keep out of reach of children