Dexmeda Ingredients and Usage

The active ingredient is Dexmedetomidine Hydrochloride, a potent alpha-2 adrenergic receptor agonist. The solution is administered as continuous intravenous infusion in monitored settings.

Dexmeda is clinically indicated for:

How Does Dexmeda Work?

Dexmeda provides sedation and analgesia through central alpha-2 receptor activation:

1. Locus Coeruleus Inhibition: Reduces norepinephrine release in brain
2. Spinal Cord Action: Modulates pain transmission pathways
3. Sympathetic Suppression: Decreases heart rate and blood pressure
4. Conscious Sedation: Patients remain rousable and cooperative

Dexmeda Side Effects and Warnings

Common side effects include hypotension, bradycardia, and dry mouth. Most cardiovascular effects are predictable and manageable.

Serious Considerations

1. Hemodynamic Monitoring: Continuous blood pressure and heart rate monitoring
2. Bradycardia Risk: May require intervention or discontinuation
3. Withdrawal Syndrome: Taper gradually after prolonged infusion
4. Hepatic Impairment: Dose reduction needed in severe liver disease
5. Drug Interactions: Potentiates effects of other sedatives and anesthetics

Dexmeda Storage Conditions

Dexmeda Injection requires proper storage handling:

• Store at room temperature below 25°C
• Protect from light and freezing
• Use diluted solution within 24 hours
• Discard if solution appears discolored or contains particles
• Follow strict aseptic preparation guidelines