ManufacturerHigh-Q Pharmaceuticals Pakistan
Active IngredientsCiprofloxacin and Nitazoxanide
Medicine Strength500mg Ciprofloxacin + 500mg Nitazoxanide per Tablet
FormulationFilm-Coated Tablets
Requires Prescription?Yes
GenericsCiprofloxacin + Nitazoxanide

Cipol-N Ingredients and Usage

The active ingredients are Ciprofloxacin (fluoroquinolone antibiotic) and Nitazoxanide (antiprotozoal agent). The combination tablet is taken orally with food for gastrointestinal infections.

Cipol-N is clinically indicated for:

  • Bacterial diarrhea and gastroenteritis
  • Protozoal infections including giardiasis
  • Mixed bacterial and parasitic gastrointestinal infections
  • Traveler’s diarrhea management

How Does Cipol-N Work?

Cipol-N provides dual antimicrobial action through different mechanisms:

  1. DNA Gyrase Inhibition: Ciprofloxacin blocks bacterial DNA replication
  2. Pyruvate Fermentation Interference: Nitazoxanide disrupts parasite energy metabolism
  3. Broad Spectrum Coverage: Targets both bacterial and protozoal pathogens
  4. Synergistic Action: Combined effect enhances treatment efficacy

Cipol-N Side Effects and Warnings

Common side effects include nausea, abdominal pain, headache, and dizziness. Most reactions are mild and self-limiting.

Serious Considerations

  1. Tendon Damage: Ciprofloxacin may cause tendonitis and tendon rupture
  2. CNS Effects: Risk of seizures, dizziness and psychiatric reactions
  3. Hypersensitivity: Serious allergic reactions including anaphylaxis
  4. Drug Interactions: Antacids and iron supplements reduce absorption
  5. Hepatic Impairment: Use with caution in patients with liver disease

Cipol-N Storage Conditions

Cipol-N Tablets require proper storage conditions:

  • Store at room temperature below 30°C
  • Keep in original packaging, protected from moisture
  • Protect from light and excessive heat
  • Keep out of reach of children
  • Do not use after the expiration date
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